IL-4, canine recombinant (rcaIL-4)

Produced in Yeast. Amino acid sequence: HNFNITIKEI IKMLNILTAR NDSCMELTVK DVFTAPKNTS DKEIFCRAAT VLRQIYTHNC SNRYLRGLYR NLSSMANKTC SMNEIKKSTL KDFLERLKVI MQKKYYRH (108). Protein function: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. [The UniProt Consortium]