IL-2 (human), animal free recombinant

Product Description: IL-2 stands out as a potent immunoregulatory lymphokine generated by T cells following antigenic or mitogenic stimulation. Its signaling through IL-2R is critical for T cell proliferation and other vital immune response activities. IL-2 plays a pivotal role in stimulating the growth and differentiation of various immune cells like B cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages, and oligodendrocytes. The recombinant Human IL-2 is a 15.5 kDa protein composed of 134 amino acid residues, featuring one intrachain disulfide bond.. Amino acid sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT. Endotoxin concentration: <0.1 EU/µg. Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is = 0.1 ng/ml, corresponding to a specific activity of > 1 x 10^7 units/mg. Contains no preservative. Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. [The UniProt Consortium]