IL-15, Swine

Sequence: TWQHVISDLK KIEDLIRSIH MDATLYTESD AHPNCKVTAM KCFLLELRVI LQESRNSDIS DTVENLIILA NSSLSSIEYK TESGCKECEE FLKSFIHIVQ with polyhistidine tag at the N-terminus Endotoxin level: <0.01 EU per 1 µg of the protein by the LAL method. Protein function: Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA. In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation. [The UniProt Consortium]