IL-15, Mouse

Sequence: NWIDVRYDLE KIESLIQSIH IDTTLYTDSD FHPSCKVTAM NCFLLELQVI LHEYSNMTLN ETVRNVLYLA NSTLSSNKNV AESGCKECEE TEFLQSFIRI with polyhistidine tag at the N-terminus Endotoxin level: <0.1 EU per 1 µg of the protein by the LAL method. Protein function: Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha. In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation. [The UniProt Consortium]