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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-RPCB1721.100 | 100 µg | - | - | - |
9 - 20 business days* |
1,161.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Endotoxin level: Less than 1EU per µg by the LAL method. Protein function: Regulates food intake,... more
Product information "GDF15 Protein (recombinant human)"
Endotoxin level: Less than 1EU per µg by the LAL method. Protein function: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL- expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling. [The UniProt Consortium]
| Keywords: | NRG-1, NAG-1, MIC-1, GDF-15, Placental TGF-beta, NSAID-regulated gene 1 protein, NSAID-activated gene 1 protein, Prostate differentiation factor, Macrophage inhibitory cytokine 1, Growth/differentiation factor 15, Placental bone morphogenetic protein |
| Supplier: | Assay Genie |
| Supplier-Nr: | RPCB1721 |
Properties
| Conjugate: | No |
| Host: | E.coli |
| Species reactivity: | human |
| Purity: | >95% (TrisBis PAGE) |
Database Information
| KEGG ID : | K05504 | Matching products |
| UniProt ID : | Q99988 | Matching products |
| Gene ID : | GeneID 9518 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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