FLT3 Ligand (human) (rec.) (His)

FLT3 Ligand (human) (rec.) (His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-HF-201FLT3L-C010 10 µg - -

3 - 9 business days*

248.00€
 
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of... more
Product information "FLT3 Ligand (human) (rec.) (His)"
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.
Keywords: Flt3L, FLT3LG, SL cytokine, Flt3 ligand, Fms-related tyrosine kinase 3 ligand, FLT3L, FMS-like Tyrosine Kinase 3 Ligand
Supplier: Chimerigen Laboratories
Supplier-Nr: HF-201FLT3L

Properties

Application: Bioassays
Conjugate: No
Host: Human cells
Species reactivity: human
MW: ~25 kD
Purity: >95%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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