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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CHI-HF-201FLT3L-C010 | 10 µg | - | - |
3 - 9 business days* |
248.00€
|
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of... more
Product information "FLT3 Ligand (human) (rec.) (His)"
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.
Keywords: | Flt3L, FLT3LG, SL cytokine, Flt3 ligand, Fms-related tyrosine kinase 3 ligand, FLT3L, FMS-like Tyrosine Kinase 3 Ligand |
Supplier: | Chimerigen Laboratories |
Supplier-Nr: | HF-201FLT3L |
Properties
Application: | Bioassays |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | ~25 kD |
Purity: | >95% |
Format: | Lyophilized |
Database Information
KEGG ID : | K05454 | Matching products |
UniProt ID : | P49771 | Matching products |
Gene ID | GeneID 2323 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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