Fibroblast Growth Factor 4, active (FGF4), Recombinant, Human

Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. {ECO:0000269, PubMed:8663044}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF­receptors transfected BaF3 cells is less than 0.5ng/ml, corresponding to a specific activity of ? 2.0x10e6 IU/mg. Sequence: GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL, Molecular Weight: 19.8kD, PubMed ID: 18192227, 2959959, 2953031, 2957062, 8663044, 20094046, 11486033, Gene Name: FGF4,HST,HSTF1,KS3, Swiss Prot: P08620, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.