Fas Ligand (FasL, TNFSF6, CD178, CD95L), swine recombinant (rpoFasLigand)

Produced in Yeast. Amino acid sequence: QIGHPNLPSE KKELRKVAHL TGKPNSRSIP LEWEDTYGIA LVSGVKYMKG SLVINDTGLY FVYSKVYFRG QYCNNQPLSH KVYTRNSRYP QDLVLMEGKM MNYCTTGQMW ARSSYLGAVF NLTSADHLYV NVSELSLVNF EESKTFFGLY KL (152). Protein function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. [The UniProt Consortium]