Eotaxin-1 (CCL11) Recombinant (Human)

Recombinant human eotaxin-1 (CCL11), full-length of mature protein, encompassing amino acids 24-97. This construct is tag-free and was affinity purified. Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils .