Cyr61/CCN1 Protein (recombinant human)

Cyr61/CCN1 Protein (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB0428.10 10 µg - - -

10 - 15 business days*

154.00€
 
Endotoxin level: < 0.1 EU/µg. Protein function: Promotes cell proliferation, chemotaxis,... more
Product information "Cyr61/CCN1 Protein (recombinant human)"
Endotoxin level: < 0.1 EU/µg. Protein function: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CCN1-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3. [The UniProt Consortium]
Keywords: IBP-10, IGFBP-10, Protein GIG1, Protein CYR61, CCN family member 1, IGF-binding protein 10, Cysteine-rich angiogenic inducer 61, Cellular communication network factor 1, Insulin-like growth factor-binding protein 10
Supplier: Assay Genie
Supplier-Nr: RPCB0428

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
Purity: >95% (SDS-PAGE)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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