CXCL4 Protein, Mouse, Recombinant (hFc)

Description: Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. CXCL4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 35 kDa and the accession number is Q9Z126. References: Ruytinx P, et al. CXCL4 and CXCL4L1 in cancer. Cytokine. 2018 Sep,109:65-7doi: 10.1016/j.cyto.2018.02.022. PMID: 29903575.