Chromosome 19 Open Reading Frame 10 (IL-25, SF20), mouse recombinant (rmC19orf10)

Mouse recombinant Chromosome 19 Open Reading Frame 10 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 143 amino acids and having a molecular mass of 15.8kDa. Mouse SF20 is a bone marrow stroma-derived growth factor. SF20 is expressed in the bone marrow, spleen stroma cells, resting mononuclear cells, resting CD8 and CD19 cells and activated CD8 T-cells. SF20 has been shown to bind to the surface of cells expressing the receptor TSA-1 (Thymic shared Ag-1). Among SF20´s biological activities is stimulation of the proliferation of FDCP2 cells (a mouse factor-dependent hemopoietic cell line) and mouse lymphoid cells.