Calcitonin gene-related peptide 2 Protein (recombinant human)

Protein Construction: Recombinant Human Calcitonin gene-related peptide 2 is produced by our Mammalian expression system and the target gene encoding Ala26&Ala82-Phe118 is expressed with a Fc tag at the C-terminus. Sequence: Ala26&Ala82-Phe118. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 25-28 kDa. Protein function: CALCB is a member of the calcitonin family. CALCB is produced in both peripheral and central neurons. It is a potent peptide vasodilator and can function in the transmission of pain. In the spinal cord, the function and expression of CGRP may differ depending on the location of synthesis. CALCB is derived mainly from the cell bodies of motor neurons when synthesized in the ventral horn of the spinal cord and may contribute to the regeneration of nervous tissue after injury. Protein function: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. [The UniProt Consortium]