Biotinylated Recombinant Human VEGF-A/VEGF165 Protein

Biotinylated Recombinant Human VEGF-A/VEGF165 Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB0027.100 100 µg - - -

9 - 20 business days*

1,258.00€
 
Endotoxin level: < 1 EU/µg of the protein by LAL method. Protein function: Growth factor active... more
Product information "Biotinylated Recombinant Human VEGF-A/VEGF165 Protein"
Endotoxin level: < 1 EU/µg of the protein by LAL method. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor (PubMed:17446437). [The UniProt Consortium]
Keywords: VPF, VEGF, VEGFA, VEGF-A, Vascular permeability factor, Vascular endothelial growth factor A
Supplier: Assay Genie
Supplier-Nr: RPCB0027

Properties

Conjugate: Biotin
Species reactivity: human
Purity: >95% (TrisBis PAGE)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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