Activin A, Recombinant, Human/Mouse/Rat, aa311-426 (Activin A GMP, INHBA)

Activin A, Recombinant, Human/Mouse/Rat, aa311-426 (Activin A GMP, INHBA)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
145698.10 10 µg - -

3 - 19 business days*

871.00€
 
Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally... more
Product information "Activin A, Recombinant, Human/Mouse/Rat, aa311-426 (Activin A GMP, INHBA)"
Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Activin proteins have a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and roles in reproductive physiology. Activin isoforms and other members of the TGF-beta superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits. Five beta subunits (mammalian beta A, beta B, beta C, beta E and Xenopus beta D) have been cloned to date. The activin/inhibin nomenclature reflects the subunit composition of the proteins: Activin A (beta A -beta A), Activin B (beta B - beta B), Activin AB (beta A - beta B), Inhibin A (alpha-beta A) and Inhibin B (alpha-beta B). , Source:, Recombinant protein corresponding to aa311-426 from human Activin A GMP, CHO-derived. Molecular Weight: ~15kD, Endotoxin: <0.10EU/1ug (LAL method), Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute in sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: 145698

Properties

Conjugate: No
Format: Highly Purified

Database Information

UniProt ID : P08476 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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