CNGA4 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1728 Sequence: ATGAGCCAGG ACACCAAAGT GAAGACAACA GAGTCCAGTC CCCCAGCCCC ATCCAAGGCC AGGAAGTTGC TGCCTGTCCT GGACCCATCT GGGGATTACT ACTACTGGTG GCTGAACACA ATGGTCTTCC CAGTCATGTA TAACCTCATC ATCCTCGTGT GCAGAGCCTG CTTCCCCGAC TTGCAGCACG GTTATCTGGT GGCCTGGTTG GTGCTGGACT ACACGAGTGA CCTGCTATAC CTACTAGACA TGGTGGTGCG CTTCCACACA GGATTCTTGG AACAGGGCAT CCTGGTGGTG GACAAGGGTA GGATCTCGAG TCGCTACGTT CGCACCTGGA GTTTCTTCTT GGACCTGGCT TCCCTGATGC CCACAGATGT GGTCTACGTG CGGCTGGGCC CGCACACACC CACCCTGAGG CTGAACCGCT TTCTCCGCGC GCCCCGCCTC TTCGAGGCCT TCGACCGCAC AGAGACCCGC ACAGCTTACC CAAATGCCTT TCGCATTGCC AAGCTGATGC TTTACATTTT TGTCGTCATC CATTGGAACA GCTGCCTATA CTTTGCCCTA TCCCGGTACC TGGGCTTCGG GCGTGACGCA TGGGTGTACC CGGACCCCGC GCAGCCTGGC TTTGAGCGCC TGCGGCGCCA GTACCTCTAT AGCTTTTACT TCTCCACGCT GATACTGACT ACAGTGGGCG ATACACCGCC GCCAGCCAGG GAAGAAGAGT ACCTCTTCAT GGTGGGCGAC TTCCTGCTGG CCGTCATGGG TTTCGCCACC ATCATGGGTA GCATGAGCTC TGTCATCTAC AACATGAACA CTGCAGATGC GGCTTTCTAC CCAGATCATG CACTGGTGAA GAAGTACATG AAGCTGCAGC ACGTCAACCG CAAGCTGGAG CGGCGAGTTA TTGACTGGTA TCAGCACCTG CAGATCAACA AGAAGATGAC CAACGAGGTA GCCATCTTAC AGCACTTGCC TGAGCGGCTG CGGGCAGAAG TGGCTGTGTC TGTGCACCTG TCCACTCTGA GCCGGGTGCA GATCTTTCAG AACTGTGAGG CCAGCCTGCT GGAGGAGCTG GTGCTGAAGC TGCAGCCCCA GACCTACTCA CCAGGTGAAT ATGTATGCCG CAAAGGAGAC ATTGGCCAAG AGATGTACAT CATCCGAGAG GGTCAACTGG CCGTGGTGGC AGATGATGGT ATCACACAGT ATGCTGTGCT CGGTGCAGGG CTCTACTTTG GGGAGATCAG CATCATCAAC ATCAAAGGGA ACATGTCTGG GAACCGCCGC ACAGCCAACA TCAAGAGCCT AGGTTATTCA GACCTATTCT GCCTGAGCAA GGAGGACCTG CGGGAGGTGC TGAGCGAGTA TCCACAAGCA CAGACCATCA TGGAGGAGAA AGGACGTGAG ATCCTGCTGA AAATGAACAA GTTGGACGTG AATGCTGAGG CAGCTGAGAT CGCCCTGCAG GAGGCCACAG AGTCCCGGCT ACGAGGCCTA GACCAGCAGC TGGATGATCT ACAGACCAAG TTTGCTCGCC TCCTGGCTGA GCTGGAGTCC AGCGCACTTA AGATTGCTTA CCGCATTGAA CGGCTGGAGT GGCAGACTCG AGAGTGGCCA ATGCCCGAGG ACCTGGCTGA GGCTGATGAC GAGGGTGAGC CTGAGGAGGG AACTTCCAAA GATGAAGAGG GCAGGGCCAG CCAGGAGGGA CCCCCAGGTC Protein function: Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection. [The UniProt Consortium]