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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay40125-1 | 1 mg | - |
6 - 10 business days* |
435.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Acetazolamide-d3 is intended for use as an internal standard for the quantification of... more
Product information "Acetazolamide-d3"
Acetazolamide-d3 is intended for use as an internal standard for the quantification of acetazolamide by GC- or LC-MS. Acetazolamide is an inhibitor of carbonic anhydrase I (CAI), CAII, CAIX, and CAXII (Kis = 310, 12, 25, and 5.7 nM, respectively, for the human enzymes). It inhibits the migration and invasion of Caki-1, Caki-2, and ACHN renal carcinoma cells when used at a concentration of 10 µM. Acetazolamide (5.6 mg/kg per day) increases currents in calcium-activated potassium channels in patch clamp assays using skeletal muscle tissues isolated from potassium-deficient rats. It induces vasodilation and increases cerebral, renal, and hepatic blood flow and blood oxygen levels in normotensive rabbits when administered at a dose of 12 mg/kg. Formulations containing acetazolamide have been used in the treatment of edema, open-angle glaucoma, epilepsy, and acute mountain sickness.Formal Name: N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-acetamide-2,2,2-d3. CAS Number: 1189904-01-5. Molecular Formula: C4H3D3N4O3S2. Formula Weight: 225.3. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Methanol: soluble. SMILES: NS(C1=NN=C(NC(C([2H])([2H])[2H])=O)S1)(=O)=O. InChi Code: InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)/i1D3. InChi Key: BZKPWHYZMXOIDC-FIBGUPNXSA-N.
Keywords: | N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-acetamide-2,2,2-d3 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 40125 |
Properties
Application: | GC-MS, LC-MS internal standard, quantification, carbonic anhydrase I, II, IX, XII inhibitor |
MW: | 225.3 D |
Formula: | C4H3D3N4O3S2 |
Purity: | >99% deuterated forms (d1-d3) |
Format: | Solid |
Database Information
CAS : | 1189904-01-5| Matching products |
KEGG ID : | K01672 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H302, H312, H315, H319, H332, H361 |
P Phrases: | P201, P202, P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P308+313, P312, P321, P330, P332+313, P337+313, P361+364, P362+364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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