PtdIns-(4,5)-P2 (1,2-dihexanoyl) (sodium salt)

PtdIns-(4,5)-P2 (1,2-dihexanoyl) (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007762-100 100 µg -

5 - 10 business days*

63.00€
Cay10007762-500 500 µg -

5 - 10 business days*

282.00€
Cay10007762-1 1 mg -

5 - 10 business days*

500.00€
 
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane... more
Product information "PtdIns-(4,5)-P2 (1,2-dihexanoyl) (sodium salt)"
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 (1,2-dihexanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of PtdIns-4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade. Formal Name: 1-(1,2-dihexanoylphosphatidyl)inositol-4,5-bisphosphate, trisodium salt. Synonyms: DHPI-4,5-P2, Phosphatidylinositol-4,5-bisphosphate C-6. Molecular Formula: C21H38O19P3 . 3Na. Formula Weight: 756.4. Purity: >98%. Formulation: A lyophilized powder. SMILES: CCCCCC(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP([O])(O)=O)[C@H]1O)([O-])=O)OC(CCCCC)=O)=O.[Na+].[Na].[Na+]. InChi Code: InChI=1S/C21H41O19P3.3Na/c1-3-5-7-9-14(22)35-11-13(37-15(23)10-8-6-4-2)12-36-43(33,34)40-19-16(24)17(25)20(38-41(27,28)29)21(18(19)26)39-42(30,31)32,,,/h13,16-21,24-26H,3-12H2,1-2H3,(H,33,34)(H2,27,28,29)(H2,30,31,32),,,/q,3*+1/p-3/t13-,16-,17+,18+,1. InChi Key: RLSRPPXCLVFTHW-JORWXVKOSA-K. Side Chain Carbon Sum: 12:0.
Keywords: DHPI-4,5-P2, Phosphatidylinositol-4,5-bisphosphate C-6, 1-(1,2-dihexanoylphosphatidyl)inositol-4,5-bisphosphate, trisodium salt
Supplier: Cayman Chemical
Supplier-Nr: 10007762

Properties

Application: Bioactive lipid assays
MW: 756.4 D
Formula: C21H38O19P3 . 3Na
Purity: >98%
Format: Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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