Leukotriene D4 methyl ester

Leukotriene D4 methyl ester
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007165-25 25 µg -

3 - 10 business days*

148.00€
Cay10007165-50 50 µg -

3 - 10 business days*

280.00€
Cay10007165-100 100 µg -

3 - 10 business days*

532.00€
 
Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis... more
Product information "Leukotriene D4 methyl ester"
Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by gamma-glutamyl transpeptidase. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. LTD4 is several hundred fold more potent than LTC4 at the cysteinyl-leukotriene 1 (CysLT1) receptor, but they exhibit approximately equal affinity at the CysLT2 receptor. LTD4 methyl ester is a more lipid soluble form of LTD4. The biological activity of LTD4 methyl ester has not been reported. Formal Name: 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid, methyl ester. Molecular Formula: C26H42N2O6S. Formula Weight: 510.7. Purity: >97%. Formulation: A solution in ethanol. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 1 mg/ml, PBS (pH 7.2): .15 mg/ml. lambdamax: 280 nm. SMILES: CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](N)C(NCC(O)=O)=O)[C@@H](O)CCCC(OC)=O. InChi Code: InChI=1S/C26H42N2O6S/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-23(22(29)16-15-18-25(32)34-2)35-20-21(27)26(33)28-19-24(30)31/h7-8,10-14,17,21-23,29H,3-6,9,15-16,18-20,27H2,1-2H3,(H,28,33)(H,30,31)/b8-7-,11-10-,13-12+,17-14+/t21-,22-,23+/m0/s1. InChi Key: PVGJCQKBOXAJIF-HXDOPMNESA-N.
Keywords: 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid, methyl ester
Supplier: Cayman Chemical
Supplier-Nr: 10007165

Properties

Application: Bioactive lipid assays
MW: 510.7 D
Formula: C26H42N2O6S
Purity: >97%
Format: Solution

Database Information

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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