Delta12-Prostaglandin D2

Delta12-Prostaglandin D2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay12650-500 500 µg -

6 - 10 business days*

48.00€
Cay12650-1 1 mg -

6 - 10 business days*

90.00€
Cay12650-5 5 mg -

6 - 10 business days*

380.00€
Cay12650-10 10 mg -

6 - 10 business days*

665.00€
 
Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from... more
Product information "Delta12-Prostaglandin D2"
Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, hematopoietic-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. Delta12-PGD2 is one of the initial chemical decomposition products of PGD2. Delta12-PGD2 is an intermediate in the pathway leading to Delta12-PGJ2, which is a cyclopentenone prostaglandin with antimitotic and carcinogenic activities. The metabolism of Delta12-PGD2 involves addition of thiol nucleophiles, as is the case with the majority of cyclopentenone prostaglandins. Formal Name: 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,12E-dien-1-oic acid. CAS Number: 64072-89-5. Synonyms: Delta12-PGD2. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 2 mg/ml. lambdamax: 245 nm. SMILES: CCCCCC(O)C/C=C1/C(=O)CC(O)C/1C/C=C\CCCC(=O)O. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,13,15-16,18,21-22H,2-3,5-6,8-12,14H2,1H3,(H,24,25)/b7-4-,17-13+/t15-,16+,18-/m0/s1. InChi Key: OBTVQKDILGZFPY-WBYUMCMISA-N.
Keywords: Delta12-PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,12E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 12650

Properties

Application: Bioactive lipid assays
MW: 352.5 D
Formula: C20H32O5
Purity: >98%
Format: Solution

Database Information

CAS : 64072-89-5| Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336
P Phrases: P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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