D-myo-Inositol-2,5,6-triphosphate (sodium salt)

D-myo-Inositol-2,5,6-triphosphate (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008424-100 100 µg -

5 - 10 business days*

62.00€
Cay10008424-500 500 µg -

5 - 10 business days*

277.00€
Cay10008424-1 1 mg -

5 - 10 business days*

490.00€
 
Ins(2,5,6)P3 (sodium salt) is a member of the inositol phosphate (InsP) family of second... more
Product information "D-myo-Inositol-2,5,6-triphosphate (sodium salt)"
Ins(2,5,6)P3 (sodium salt) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of the Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of calcium channels and an increase in intracellular calcium. Ins(2,5,6)P3 is a less potent inducer of calcium release from permeabilized rat basophilic leukemia cells with an EC50 value of 110 µM compared to Ins(1,4,5)P3, which has an EC50 value of 0.17 µM. Formal Name: D-myo-inositol-2,5,6-tris(dihydrogen phosphate), trisodium salt. Synonyms: Ins(2,5,6)P3 (sodium salt), 2,5,6-IP3 (sodium salt). Molecular Formula: C6H12O15P3 . 3Na. Formula Weight: 486.0. Purity: >98%. Formulation: A lyophilized powder. Solubility: PBS (pH 7.2): 50 mg/ml, Water:. SMILES: O[C@@H]1[C@@H](O)[C@@H](OP([O-])(O)=O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@H]1OP([O-])(O)=O.[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C6H15O15P3.3Na/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12,,,/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18),,,/q,3*+1/p-3/t1-,2-,3-,4?,5?,6?,,,/m1.../s1. InChi Key: ZVCVTWVBDIPWPZ-XIEXOYEMSA-K.
Keywords: 2,5,6-IP3 (sodium salt), Ins(2,5,6)P3 (sodium salt), D-myo-inositol-2,5,6-tris(dihydrogen phosphate), trisodium salt
Supplier: Cayman Chemical
Supplier-Nr: 10008424

Properties

Application: Bioactive lipid assays
MW: 486 D
Formula: C6H12O15P3 . 3Na
Purity: >98%
Format: Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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