CAY10434

CAY10434
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10005067-1 1 mg -

6 - 10 business days*

24.00€
Cay10005067-5 5 mg -

6 - 10 business days*

108.00€
Cay10005067-10 10 mg -

6 - 10 business days*

190.00€
Cay10005067-50 50 mg -

6 - 10 business days*

832.00€
 
20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the... more
Product information "CAY10434"
20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. Alkylaryl imidazoles have been previously shown to inhibit certain CYP450 enzymes, including the CYP4A enzymes associated with 20-HETE synthesis. CAY10434 is a selective inhibitor of the 20-HETE synthase CYP4A11 exhibiting an IC50 value of 8.8 nM when tested in human renal microsomes. CAY10434 is nearly 200 times less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes. Formal Name: 6-[4-(1H-imidazol-1-yl)phenoxy]-N,N-dimethyl-1-hexanamine. CAS Number: 769917-29-5. Molecular Formula: C17H25N3O. Formula Weight: 287.4. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: 20 mg/ml, DMf:PBS (pH 7.2)(1:3): .2 mg/ml, DMSO: 12 mg/ml, Ethanol: 15 mg/ml. lambdamax: 203, 242 nm. SMILES: CN(C)CCCCCCOC1=CC=C(N2C=CN=C2)C=C1. InChi Code: InChI=1S/C17H25N3O/c1-19(2)12-5-3-4-6-14-21-17-9-7-16(8-10-17)20-13-11-18-15-20/h7-11,13,15H,3-6,12,14H2,1-2H3. InChi Key: FIFQJYUSSPRJIZ-UHFFFAOYSA-N.
Keywords: 6-[4-(1H-imidazol-1-yl)phenoxy]-N,N-dimethyl-1-hexanamine
Supplier: Cayman Chemical
Supplier-Nr: 10005067

Properties

Application: CYP4A11 inhibitor
MW: 287.4 D
Formula: C17H25N3O
Purity: >98%
Format: Solution

Database Information

CAS : 769917-29-5| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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