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1,2-Dipalmitoyl-13C-sn-glycero-3-PC
Item number: Cay29133-1
1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC (Cay-10009473) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and...
| Keywords: | 1,2-Dihexadecanoyl-13C-sn-glycero-3-Phosphatidylcholine, 1,2-Dihexadecanoyl-13C-sn-glycero-3-Phosphocholine,... |
| Application: | GC-MS, LC-MS, internal standard, quantification |
| CAS | 65277-91-0 |
| MW: | 736 D |
From 93.00€
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15(S)-HETE-d8 ethyl ester
Item number: Cay30578-100
15(S)-HETE-d8 ethyl ester is intended for use as an internal standard for the quantification of 15-HETE ethyl ester by GC- or LC-MS. 15(S)-HETE ethyl ester is an esterified form of 15(S)-HETE (Cay-34720), a major metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) via the 15-lipoxygenase pathway....
| Keywords: | 15(S)-Hydroxyeicosatetraenoic Acid-d8 ethyl ester, 15(S)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic-5,6,8,9,11,12,14,15-d8... |
| Application: | Internal standard, quantification, LC-MS, GC-MS |
| MW: | 356.6 D |
From 265.00€
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PTIQ
Item number: Cay33540-100
PTIQ is a neuroprotective compound. It inhibits tetrahydro-L-biopterin-induced cytotoxicity and increases in matrix metalloproteinase-3 (MMP-3) levels in CATH.a cells (IC50s = 1.8 and 0.06 µM, respectively). PTIQ inhibits LPS-induced production of MMP-3, TNF-alpha, and COX-2 in BV-2 microglia (IC50s = 2.4, 6.5, and...
| Keywords: | 1-(3,4-dihydro-7-hydroxy-6-methoxy-2(1H)-isoquinolinyl)-1-propanone |
| Application: | Neuroprotective compound |
| CAS | 1032822-42-6 |
| MW: | 235.3 D |
From 147.00€
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Drospirenone-13C3
Item number: Cay34008-1
Drospirenone-13C3 is intended for use as an internal standard for the quantification of drospirenone (Cay-23347) by GC- or LC-MS. Drospirenone is a synthetic progestogen. In vivo, drospirenone inhibits spontaneous ovulation in rats (ID50s = 0.3-1.0 mg/day) when administered orally or subcutaneously. Drospirenone...
| Keywords: | 1,2-dihydro Spirorenone-13C3, ZK 30595-13C3,... |
| Application: | GC-MS, LC-MS, internal standard, quantification, aldosterone antagonist |
| MW: | 369.5 D |
From 295.00€
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1-1(Z)-Hexadecenyl-2-Arachidonoyl-sn-glycero-3-PC
Item number: Cay34182-1
1-1(Z)-Hexadecenyl-2-arachidonoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-hexadecenoic acid and arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) at the sn-1 and sn-2 positions, respectively. Serum levels of 1-1(Z)-hexadecenyl-2-arachidonoyl-sn-glycero-3-PC are decreased in dogs with myxomatous...
| Keywords: | 1-1(Z)-Hexadecenyl-2-Arachidonoyl-sn-glycero-3-Phosphatidylcholine,... |
| Application: | Plasmalogen |
| CAS | 84460-45-7 |
| MW: | 766.1 D |
From 118.00€
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21-Deoxycortisone
Item number: Cay35236-10
21-Deoxycortisone is a corticosteroid metabolite of 11-keto progesterone. It is formed from 11-keto progesterone by the cytochrome P450 (CYP) isoform CYP17A1, but can also be produced via oxidation of 21-deoxycortisol (Cay-30873) by 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2). Levels of...
| Keywords: | 21-Desoxycortisone, NSC 38722, 17-hydroxy-pregn-4-ene-3,11,20-trione |
| Application: | 11-keto progesterone corticosteroid metabolite |
| CAS | 1882-82-2 |
| MW: | 344.5 D |
From 88.00€
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Epigoitrin
Item number: Cay35620-10
Epigoitrin is an alkaloid that has been found in Crambe abyssinica and has diverse biological activities. It decreases norepinephrine formation by bovine dopamine-beta-hydroxylase in a cell-free assay when used at a concentration of 0.1 mM. Epigoitrin inhibits the proliferation of RAW 264.7 macrophages (IC50 = ~1...
| Keywords: | (R)-Goitrin, Ba 51-090278, (5R)-5-ethenyl-2-oxazolidinethione |
| Application: | Alkaloid |
| CAS | 1072-93-1 |
| MW: | 129.2 D |
From 75.00€
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Salvigenin
Item number: Cay35632-1
Salvigenin is a polyphenol flavonoid originally found in Alnus japonica with diverse biological activities. It inhibits hydrogen peroxide-induced apoptosis and reduces the generation of reactive oxygen species (ROS) in SH-SY5Y human neuroblastoma cells when used at a concentration of 25 µM. Salvigenin (25 and 50 µM)...
| Keywords: | 5-hydroxy-4',6,7-Trimethoxyflavone, 7-O-Methylpectolinarigenin, Psathyrotin,... |
| Application: | Bioactive polyphenol flavonoid |
| CAS | 19103-54-9 |
| MW: | 328.3 D |
From 95.00€
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6alpha-Methylprednisolone 21-acetate
Item number: Cay35799-100
6alpha-Methylprednisolone 21-acetate is a synthetic glucocorticoid and an ester form of methylprednisolone (Cay-15013). It reduces IL-1beta-induced production of prostaglandin E2 (PGE2, Cay-14010) and increases in matrix metalloproteinase-13 (MMP-13) levels in equine osteochondral and synovial explant cocultures...
| Keywords: | Methylprednisolone Acetate, MPA, NSC 48985, U-8210,... |
| Application: | Methylprednisolone ester, synthetic glucocorticoid |
| CAS | 53-36-1 |
| MW: | 416.5 D |
From 84.00€
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3-(4-Hydroxyphenyl)lactic Acid
Item number: Cay36367-100
3-(4-Hydroxyphenyl)lactic acid (HPLA) is a bacterial metabolite produced by L. murinus in the gut microbiome. Oral administration of HPLA with DL-3-phenylacetic acid (PLA), 2-hydroxyisocaproic acid (HICA), 2-hydroxy-3-methylbutyric acid (HMBA), and 1-indole-lactic acid (ILA) increases intestinal and white adipose...
| Keywords: | (±)-3-(4-Hydroxyphenyl)lactic Acid, DL-p-Hydroxyphenyllactic Acid, HPLA, beta-(4-Hydroxyphenyl)-DL-Lactic Acid,... |
| Application: | Bacterial metabolite |
| CAS | 306-23-0 |
| MW: | 182.2 D |
From 157.00€
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WHI-P97
Item number: Cay36385-1
WHI-P97 is an inhibitor of JAK3 (IC50 = 11 µM). It inhibits leukotriene C4 (LTC4) and LTB4 release, mediated by the high-affinity IgE receptor Fc epsilon receptor I (FcepsilonRI), from RBL-2H3 mast cells when used at a concentration of 10 µM. It also inhibits FcepsilonRI-mediated 5-lipoxygease (5-LO) translocation...
| Keywords: | HY-11067, 2,6-dibromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol |
| Application: | JAK3 inhibitor |
| CAS | 211555-05-4 |
| MW: | 455.1 D |
From 54.00€
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Solanidine
Item number: Cay36433-1
Solanidine is a steroidal glycoalkaloid metabolite that has been found in potato (S. tuberosum) and has anticancer and teratogenic activities. It inhibits the growth of HT-29 colon and HepG2 liver cancer cells by 80.9 and 82.2%, respectively, when used at a concentration of 100 µg/ml. Solanidine (176 mg/kg) is...
| Keywords: | (-)-Solanidine, 22R,25S-Solanidine, NSC 76025, (3beta)-solanid-5-en-3-ol |
| Application: | Steroidal glycoalkaloid metabolite, anticancer / teratogenic agent |
| CAS | 80-78-4 |
| MW: | 397.6 D |
From 149.00€
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