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(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. (±)5-HETE lactone is an inhibitor of 5-lipoxygenase from rat basophilic leukemia cells with an IC50 of 27 µM. The lactone is several times more potent than the linear (±)5-HETE.Formal Name: tetrahydro-6-(1E,3Z,6Z,9Z)-1,3,6,9-pentadecatetraen-1-yl-2H-pyran-2-one. CAS Number: 81517-87-5. Synonyms: (±)5-Hydroxyeicosatetraenoic Acid lactone. Molecular Formula: C20H30O2. Formula Weight: 302.5. Purity: >98%. Formulation: (Request formulation change), A solution in acetonitrile. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 1 mg/ml. lambdamax: 236 nm. SMILES: CCCCC/C=C\C/C=C\C/C=C\C=C/C1CCCC(=O)O1. InChi Code: InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(21)22-19/h6-7,9-10,12-14,16,19H,2-5,8,11,15,17-18H2,1H3/b7-6-,10-9-,13-12-,16-14+. InChi Key: QZMAEYDIHWEEAF-XTDASVJISA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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