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Product information "15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide"
17-phenyl trinor PG2alpha ethyl amide is an analog of PG2alpha that is used topically for the treatment of glaucoma and ocular hypertension. 15(R)-17-phenyl trinor PG2alpha ethyl amide is an isomer of 17-phenyl trinor PG2alpha ethyl amide, characterized by an inverted (beta) hydroxyl group at C-15. While this isomer has not been characterized, the comparable inversion of 15-hydroxyl groups, from (S) to (R), on other PGF2alpha analogs typically decreases, but does not eliminate, activity.Formal Name: N-ethyl-9alpha,11alpha,15R-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide. CAS Number: 1163135-92-9. Synonyms: 15(R)-Bimatoprost, 15(R)-17-phenyl trinor PGF2alpha ethyl amide. Molecular Formula: C25H37NO4. Formula Weight: 415.6. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: Acetonitrile: 3 mg/ml, DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 0.3 mg/ml. SMILES: CCNC(=O)CCC/C=C\CC1C(O)CC(O)[C@@H]1\C=C\[C@H](O)CCc1ccccc1. InChi Code: InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21-,22-,23+,24-/m1/s1. InChi Key: AQOKCDNYWBIDND-ZPFRTTICSA-N.
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