15-deoxy-Delta12,14-Prostaglandin J2-d4

15-deoxy-Delta12,14-Prostaglandin J2-d4
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay318570-25 25 µg -

5 - 10 business days*

100.00€
Cay318570-50 50 µg -

5 - 10 business days*

190.00€
Cay318570-100 100 µg -

5 - 10 business days*

360.00€
 
15-deoxy-Delta12,14-PGJ2-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It... more
Product information "15-deoxy-Delta12,14-Prostaglandin J2-d4"
15-deoxy-Delta12,14-PGJ2-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 15-deoxy-Delta12,14-PGJ2 by GC- or LC-mass spectrometry. 15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is a metabolite of PGJ2. 15-deoxy-Delta12,14-PGJ2 is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 µM. Formal Name: 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic-3,3,4,4-d4 acid. CAS Number: 1542166-82-4. Synonyms: 15-deoxy-Delta12,14-PGJ2-d4. Molecular Formula: C20H24D4O3. Formula Weight: 320.5. Purity: >99% deuterated forms (d1-d4). Formulation: A solution in methyl acetate. Solubility: DMF: >100 mg/ml (from PGD2), DMSO: >50 mg/ml (from PGD2), Ethanol: >75 mg/ml (from PGD2), PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12,. lambdamax: 306 nm. SMILES: O=C1/C([C@@H](C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)C=C1)=C/C=C/CCCCC. InChi Code: InChI=1S/C20H28O3/c1-2-3-4-5-6-10-13-18-17(15-16-19(18)21)12-9-7-8-11-14-20(22)23/h6-7,9-10,13,15-17H,2-5,8,11-12,14H2,1H3,(H,22,23)/b9-7-,10-6+,18-13+/t17-/m0/s1/i8D2,11D2. InChi Key: VHRUMKCAEVRUBK-NSTSLKHFSA-N.
Keywords: 15-deoxy-Delta12,14-PGJ2-d4, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic-3,3,4,4-d4 acid
Supplier: Cayman Chemical
Supplier-Nr: 318570

Properties

Application: Standard
MW: 320.5 D
Formula: C20H24D4O3
Purity: >99% deuterated forms (d1-d4)
Format: Solution

Database Information

CAS : 1542166-82-4| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336
P Phrases: , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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