13,14-dihydro-15-keto Prostaglandin E2

13,14-dihydro-15-keto Prostaglandin E2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14650-1 1 mg -

6 - 10 business days*

78.00€
Cay14650-5 5 mg -

6 - 10 business days*

349.00€
Cay14650-10 10 mg -

6 - 10 business days*

620.00€
 
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is the primary metabolite of... more
Product information "13,14-dihydro-15-keto Prostaglandin E2"
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is the primary metabolite of PGE2 (Cay-14010) in plasma. Endogenous or infused PGE2 is rapidly metabolized by the enzymes 15-hydroxy PGDH and 15-oxo-PG Delta13-reductase to form 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 accumulates to detectable levels, plasma levels in humans are between 10-100 pg/ml. It undergoes further metabolism and chemical decomposition, giving it a relatively short half-life. In dogs, the plasma half-life of 13,14-dihydro-15-keto PGE2 is about 9 minutes. In humans the metabolite has a similar short half-life, making it a poor choice of analytes for assays designed to measure total PGE2 biosynthesis. Formal Name: 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid. CAS Number: 363-23-5. Synonyms: 13,14-dihydro-15-keto PGE2. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >95%. Formulation: A solution in methyl acetate. Solubility: DMF: >100 mg/ml (from PGE2), DMSO: >100 mg/ml (from PGE2), Ethanol: >100 mg/ml (from PGE2), PBS pH 7.2: >5 mg/ml (from PGE2). SMILES: O=C1[C@H](C/C=C\CCCC(O)=O)[C@@H](CCC(CCCCC)=O)[C@H](O)C1. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-17,19,23H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,19-/m1/s1. InChi Key: CUJMXIQZWPZMNQ-XYYGWQPLSA-N.
Keywords: 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 14650

Properties

Application: Bioactive lipid assays
MW: 352.5 D
Formula: C20H32O5
Purity: >95%
Format: Solution

Database Information

CAS : 363-23-5| Find alternatives
KEGG ID : K00069 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H316, H319, H336
P Phrases: , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P332+313, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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