11(S)-HETE

11(S)-HETE is an oxylipin and the (S) enantiomer of 11(R)-HETE (Cay-34505). It is formed non-enzymatically from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). Levels of 11(S)-HETE are higher than those of 11(R)-HETE in isolated human plasma and serum and in LPS-stimulated isolated human plasma. Serum labels of 11(S)-HETE decrease in patients with allergic rhinitis after one year of double-mite subcutaneous immunotherapy (DM-SCIT) and are associated with an improved quality of life in regards to rhinoconjunctivitis.Formal Name: 11S-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid. CAS Number: 54886-50-9. Synonyms: 11(S)-Hydroxyeicosatetraenoic Acid. Molecular Formula: C20H32O3. Formula Weight: 320.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.1 M Na2CO3: 2 mg/ml, DMF: Miscible, DMSO: Miscible, Ethanol: Miscible, PBS pH 7.2: 0.8 mg/ml. lambdamax: 236 nm. SMILES: CCCCC/C=C\C=C/[C@@H](O)C/C=C\C/C=C\CCCC(=O)O. InChi Code: InChI=1S/C20H32O3/c1-2-3-4-5-7-10-13-16-19(21)17-14-11-8-6-9-12-15-18-20(22)23/h6-7,9-11,13-14,16,19,21H,2-5,8,12,15,17-18H2,1H3,(H,22,23)/b9-6-,10-7-,14-11-,16-13+/t19-/m1/s1. InChi Key: GCZRCCHPLVMMJE-YZGNWCGPSA-N.