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Description: Zongertinib is a human HER2-selective tyrosine kinase inhibitor, a novel TK that is highly selective for covalent binding to the HER2 tyrosine kinase domain (TKD).Zongertinib exhibits antitumor activity with inhibitory effects on pHER2 and EGF. Target: Tyrosine Kinases, HER. Smiles: N(C=1C2=C(C=NC(=N2)N3CCC(NC(C=C)=O)CC3)N=CN1)C4=CC(C)=C(OC=5C=C6C(=CC5)N(C)C=N6)C=C4. References: Wilding Birgit, et al. Synthesis of diazino-pyrimidines as anticancer agents. WO2021213800.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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