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Item number: Cay44994-10

Zongertinib is an inhibitor of mutant HER2 containing an activating exon 20 insertion (HER2YVMA. IC50 = 13 nM in a cellular phosphorylation assay using HEK cells). It is selective for the inhibition of HER2YVMA over wild-type EGFR (IC50 = 576 nM in a cellular phosphorylation assay using HEK cells). It is also...

Keywords:	BI 1810631,...
Application:	HER2-YVMA inhibitor
CAS	2728667-27-2
MW:	535.61 D

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Zongertinib

Item number: TGM-T69534-10mg

Description: Zongertinib is a human HER2-selective tyrosine kinase inhibitor, a novel TK that is highly selective for covalent binding to the HER2 tyrosine kinase domain (TKD).Zongertinib exhibits antitumor activity with inhibitory effects on pHER2 and EGF. Target: Tyrosine Kinases, HER. Smiles:...

Keywords:	BI 1810631, BI 764532
Application:	Targets receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1] (ERBB2, HER2, CD340)
CAS	2728667-27-2
MW:	535.6 D

From 65.00€ *

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