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ZM 241385 is a potent antagonist of A2A adenosine receptors (pIC50 = 9.52 for displacement of 5'-N-ethylcarboxamidoadenosine from rat phaeochromocytoma cell membranes). It displays little or no activity at other A adenosine receptors. ZM 241385 is active in vivo. It acts as an inverse agonist at constitutively active mutants of the human A2B adenosine receptor.Formal Name: 4-[2-[[7-amino-2-(2-furanyl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]-phenol. CAS Number: 139180-30-6. Molecular Formula: C16H15N7O2. Formula Weight: 337.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 100mM, Ethanol: 5 mM. lambdamax: 228, 256 nm. SMILES: OC1=CC=C(CCNC2=NC3=NC(C4=CC=CO4)=NN3C(N)=N2)C=C1. InChi Code: InChI=1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22). InChi Key: PWTBZOIUWZOPFT-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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