111 products were found matching "K04266"!

Protein function: Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity) [The UniProt Consortium]

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ADORA2a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ADORA2a. Next,...

Adenosine A2A receptor (human recombinant) contains amino acids corresponding to the full length, wild-type, human A2A receptor, as well as N-terminal histidine and streptavidin tags with a TEV protease cleavage site. The A2A receptor is a G protein-coupled receptor (GPCR) that is activated by adenosine on...

Description: A2AR Protein-Nanodisc, Human, Recombinant (His & Flag) is expressed in HEK293 Cells. The accession number is P29274.

Description: A2AR Protein-VLP, Human, Recombinant (Flag) is expressed in HEK293 Cells. The accession number is P29274.

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. ADORA2A antibody recognizes Adenosine receptor A2A, a G protein-coupled receptor (GPCR) that mediates adenosine signaling to regulate neurotransmission, vascular tone, and immune responses. The ADORA2A gene, located on chromosome 22q11.23,...

5'-Deoxy-5'-methylthioadenosine (MTA) is an intermediate in the generation of adenine and methionine that is produced by the decarboxylation of S-adenosylmethionine. This nucleoside is a potent agonist of adenosine receptors (Kis = 0.15, 1.13, 13.9, and 0.68 µM for A1, A2A, A2B, and A3, respectively). At higher...

ZM 241385 is a potent antagonist of A2A adenosine receptors (pIC50 = 9.52 for displacement of 5'-N-ethylcarboxamidoadenosine from rat phaeochromocytoma cell membranes). It displays little or no activity at other A adenosine receptors. ZM 241385 is active in vivo. It acts as an inverse agonist at constitutively...

CGS 21680 is a potent, selective agonist of the adenosine A2A receptor (Ki = 11-46 nM). It is less effective at adenosine A1 and A3 receptors (Kis = 0.5-3.1 and 0.6-1 µM, respectively) and is without effect at adenosine A2B (Ki > 10 µM). CGS 21680 is commonly used to study the actions of the adenosine A2A receptor...

Adenosine is a purine nucleoside composed of adenine and ribose linked by a glycosidic linkage. It is an endogenous ligand of a family of four adenosine receptors, which serve diverse roles related to smooth muscle tone, central nervous system regulation, and cardiac function. Adenosine is a precursor for adenosine...

SCH 58261 is a competitive antagonist of the adenosine A2A receptor (Kis = 2.3 and 2.0 nM in rat and bovine brain, respectively). It is selective for the A2A subtype, displaying an A1/A2A selectivity ratio of 50-100-fold and does not interact with A2B or A3 receptors. SCH 58261 has been used to improve 6-hydroxy...

Xanthine amine congener (XAC) is a non-selective adenosine receptor antagonist with Kb values of 83, 25, and 15 nM for rat PC12 cells, human platelets that endogenously express adenosine A2A receptors, and rat fat cells that endogenously express A1 receptors, respectively. It reduces adenylate cyclase activity...