Ziftomenib

Item number	Size	Manual	Delivery time	Price
Cay45139-5	5 mg	-	6 - 10 business days*	438.00€
Cay45139-10	10 mg	-	6 - 10 business days*	613.00€
Cay45139-25	25 mg	-	6 - 10 business days*	985.00€
Cay45139-50	50 mg	-	6 - 10 business days*	1,533.00€

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An inhibitor of the menin-MLL1 protein-protein interaction, reduces the viability of OCI-AML-3... more

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Product information "Ziftomenib"

An inhibitor of the menin-MLL1 protein-protein interaction, reduces the viability of OCI-AML-3 and MV4-11 cells, reduces the viability of MOLM-13 cells expressing p53R175H and TP53-/- MOLM-13 cells over MOLM-13 cells expressing wild-type p53, increases survival in a PDX mouse model of AML at 75 mg/kg. SMILES: FC(F)(F)CC1=CC(C(S1)=NC(NC)=N2)=C2NC3CCN(CC4=CC=C5C(C=C(N5C[C@H](C)N6CCN(CC6)S(=O)(C)=O)C#N)=C4C)CC3. InChi Code: InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47)19-45-25(18-37)15-27-22(2)23(5-6-29(27)45)20-42-9-7-24(8-10-42)39-30-28-16-26(17-33(34,35)36)48-31(28)41-32(38-3)40-30/h5-6,15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40,41)/t21-/m0/s1. InChi Key: BGGALFIXXQOTPY-NRFANRHFSA-N

Keywords:	KO-539, 4-methyl-5-[[4-[[2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl] methyl]-1-[(2S)-2-[4-(methylsulfonyl)-1-piperazinyl]propyl]-H-indole-2-carbonitrile
Supplier:	Cayman Chemical
Supplier-Nr:	45139

Properties

Application:	Menin-MLL1 protein-protein interaction inhibitor
MW:	717.88 D
Formula:	C33H42F3N9O2S2
Purity:	>98%
Format:	Solid

Database Information

CAS :	2134675-36-6\| Matching products
KEGG ID :	K14970 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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