WRN Inhibitor 8

Item number	Size	Manual	Delivery time	Price
Cay43724-1	1 mg	-	6 - 10 business days*	216.00€
Cay43724-5	5 mg	-	6 - 10 business days*	969.00€
Cay43724-10	10 mg	-	6 - 10 business days*	1,505.00€

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WRN inhibitor 8 is an inhibitor of the DNA helicase Werner syndrome protein (WRN, IC50 = 48.3... more

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Product information "WRN Inhibitor 8"

WRN inhibitor 8 is an inhibitor of the DNA helicase Werner syndrome protein (WRN, IC50 = 48.3 nM). It inhibits the growth of HCT116 and SW480 colorectal cancer cells (GI50s = 0.01699 and 13.64 µM, respectively). SMILES FC(F)(C1CC1)C2=NC=C(C(OC3=CC=CC=C3)=N2)C(N[C@H](/C=C/S(=O)(C)=O)C4CC4)=O InChi Code InChI=1S/C22H23F2N3O4S/c1-32(29,30)12-11-18(14-7-8-14)26-19(28)17-13-25-21(22(23,24)15-9-10-15)27-20(17)31-16-5-3-2-4-6-16/h2-6,11-15,18H,7-10H2,1H3,(H,26,28)/b12-11+/t18-/m1/s1 InChi Key SGERSEZXZIVUEY-IENJSVCTSA-N

Keywords:	2-(cyclopropyldifluoromethyl)-N-[(1S,2E)-1-cyclopropyl-3-(methylsulfonyl)-2-propen-1-yl]-4-phenoxy-5-pyrimidinecarboxamide
Supplier:	Cayman Chemical
Supplier-Nr:	43724

Properties

Application:	WRN inhibitor
MW:	463.5 D
Formula:	C22H23F2N3O4S
Purity:	>95%
Format:	Solid

Database Information

CAS :	3026502-95-1\| Matching products
KEGG ID :	K10900 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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