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Item number: Cay43724-1

WRN inhibitor 8 is an inhibitor of the DNA helicase Werner syndrome protein (WRN, IC50 = 48.3 nM). It inhibits the growth of HCT116 and SW480 colorectal cancer cells (GI50s = 0.01699 and 13.64 µM, respectively). SMILES FC(F)(C1CC1)C2=NC=C(C(OC3=CC=CC=C3)=N2)C(N[C@H](/C=C/S(=O)(C)=O)C4CC4)=O InChi Code...

Keywords:	2-(cyclopropyldifluoromethyl)-N-[(1S,2E)-1-cyclopropyl-3-(methylsulfonyl)-2-propen-1-yl]-4-phenoxy-5-pyrimidinecarboxamide
Application:	WRN inhibitor
CAS	3026502-95-1
MW:	463.5 D

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