Werner Syndrome RecQ Helicase-IN-2

Item number	Size	Manual	SDS	Delivery time	Price
Cay41678-1	1 mg	-	-	5 - 10 business days*	153.00€
Cay41678-5	5 mg	-	-	5 - 10 business days*	682.00€
Cay41678-10	10 mg	-	-	5 - 10 business days*	1,211.00€
Cay41678-50	50 mg	-	-	5 - 10 business days*	4,535.00€

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An inhibitor of WRN (IC50 = 100 nM), selectively inhibits the growth of SW48 cells over... more

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Product information "Werner Syndrome RecQ Helicase-IN-2"

An inhibitor of WRN (IC50 = 100 nM), selectively inhibits the growth of SW48 cells over DLD-1-WRN-KO cells (GI50s = 100 and >10,000 nM, respectively), reduces tumor volume in an SW48 mouse xenograft model at 120 mg/kg per day. Formulation: A solid. InChI: InChI=1S/C32H34F3N9O5/c1-4-23-26(41-9-11-42(12-10-41)29(47)25-27(46)19(3)36-17-37-25)30(48)44-31(39-28(40-44)20-7-13-49-14-8-20)43(23)16-24(45)38-22-6-5-21(15-18(22)2)32(33,34)35/h5-7,15,17,46H,4,8-14,16H2,1-3H3,(H,38,45). InChIKey: FHYSHYIPBJMLRM-UHFFFAOYSA-N. SMILES: CC1=CC(C(F)(F)F)=CC=C1NC(CN(C2=NC(C3=CCOCC3)=NN24)C(CC)=C(N5CCN(C(C6=NC=NC(C)=C6O)=O)CC5)C4=O)=O

Keywords:	Werner Syndrome RecQ Helicase Inhibitor 2, WS RecQ Helicase Inhibitor 2, WS RecQ Helicase-IN-2, 2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-[4-[(5-hydroxy-6-methyl-4-pyrimidinyl)carbonyl]-1-piperazinyl]-N-[2-methyl-4-(trifluoromethyl)phenyl]-7-oxo-[1,2,4]tria
Supplier:	Cayman Chemical
Supplier-Nr:	41678

Properties

Application:	WRN inhibitor
Immunogen:	681.7
MW:	681.7 D
Formula:	C32H34F3N9O5
Purity:	>98%
Format:	Solid

Database Information

CAS :	2869954-51-6\| Matching products
KEGG ID :	K10900 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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