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Werner syndrome RecQ helicase-IN-2
Item number: TGM-T72108-25mg
Description: Werner syndrome RecQ helicase-IN-2 (example 57) is a potent inhibitor of the Werner syndrome RecQ DNA helicase enzyme (WRN) with potential for use in cancer research. Target: Others. Smiles: C(C(NC1=C(C)C=C(C(F)(F)F)C=C1)=O)N2C=3N(C(=O)C(=C2CC)N4CCN(C(=O)C=5C(O)=C(C)N=CN5)CC4)N=C(N3)C=6CCOCC6
| CAS | 2869954-51-6 |
| MW: | 681.66 D |
From 1,355.00€
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Werner Syndrome RecQ Helicase-IN-2
Item number: Cay41678-1
An inhibitor of WRN (IC50 = 100 nM), selectively inhibits the growth of SW48 cells over DLD-1-WRN-KO cells (GI50s = 100 and >10,000 nM, respectively), reduces tumor volume in an SW48 mouse xenograft model at 120 mg/kg per day. Formulation: A solid. InChI:...
| Keywords: | Werner Syndrome RecQ Helicase Inhibitor 2, WS RecQ Helicase Inhibitor 2, WS RecQ Helicase-IN-2,... |
| Application: | WRN inhibitor |
| CAS | 2869954-51-6 |
| MW: | 681.7 D |
From 153.00€
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