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UNC0646

TargetMol
UNC0646
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-TQ0232-5mg 5 mg

7 - 10 business days*

58.00€
TGM-TQ0232-1mL 1 ml

7 - 10 business days*

88.00€
TGM-TQ0232-10mg 10 mg

7 - 10 business days*

102.00€
TGM-TQ0232-25mg 25 mg

7 - 10 business days*

190.00€
TGM-TQ0232-50mg 50 mg

7 - 10 business days*

339.00€
TGM-TQ0232-100mg 100 mg

7 - 10 business days*

496.00€
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
 
Description Product Citations Certificate of Analysis Reviews 0
Description
Description: UNC0646 is a potent and selective inhibitor of the homologous protein lysine... more
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Product information "UNC0646"
Description: UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646(UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells) and exhibits low cellular toxicity (EC50: 4.7 µM in MCF7 cells). Target: Histone Methyltransferase. Smiles: COc1cc2c(NC3CCN(CC3)C3CCCCC3)nc(nc2cc1OCCCN1CCCCC1)N1CCCN(CC1)C(C)C. References: Liu F, et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem. 2011 Sep 8,54(17):6139-50.
Keywords: UNC 0646
Supplier: TargetMol
Supplier-Nr: TQ0232

Properties

Application: Potent, selective EHMT1 / EHMT2 inhibitor
MW: 621.9 D
Formula: C36H59N7O2

Database Information

CAS : 1320288-17-2| Matching products
KEGG ID : K11420 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Product Citations
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