TP0463518

TP0463518
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T5392-5mg 5 mg

7 - 10 business days*

46.00€
TGM-T5392-1mL 1 ml

7 - 10 business days*

52.00€
TGM-T5392-10mg 10 mg

7 - 10 business days*

72.00€
TGM-T5392-25mg 25 mg

7 - 10 business days*

120.00€
TGM-T5392-50mg 50 mg

7 - 10 business days*

198.00€
TGM-T5392-100mg 100 mg

7 - 10 business days*

371.00€
 
Description: TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM... more
Product information "TP0463518"
Description: TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively). Target: HIF/HIF Prolyl-Hydroxylase. Smiles: OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(Cl)cc3)nc2)C1=O. References: Kato S, et al. TP0463518, a novel inhibitor for hypoxia-inducible factor prolyl hydroxylases, increases erythropoietin in rodents and monkeys with a good pharmacokinetics-pharmacodynamics correlation. Eur J Pharmacol. 2018 Nov 5,838:138-144.
Supplier: TargetMol
Supplier-Nr: T5392

Properties

Application: Pan HIF-PH inhibitor
MW: 431.83 D
Formula: C20H18ClN3O6

Database Information

CAS : 1558021-37-6| Matching products
KEGG ID : K09592 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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