TOFA

TOFA
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-CR1-2905-M005 5 mg -

3 - 9 business days*

10 %
39.00€
35.10€
AG-CR1-2905-M025 25 mg -

3 - 9 business days*

10 %
154.00€
138.60€
 
Fatty acid synthase (FASN) inhibitor. Cell permeable, potent, reversible and competitive... more
Product information "TOFA"
Fatty acid synthase (FASN) inhibitor. Cell permeable, potent, reversible and competitive inhibitor of acetyl-CoA carboxylase (ACC) consequently blocking the synthesis of malonyl-CoA. Useful agent for immunometabolism research. Anticancer agent. Induces apoptosis in a variety of tumor cell lines. Relatively non-cytotoxic to various cancer cell lines. TOFA-induced reduction in malonyl-CoA is reported to off-set the effect of C75 (AG-CR1-2904) on food intake in fasted mice and on apoptosis in tumor cells. Hypolipidemic agent. Stimulates citrate accumulation in the cell, which leads to a suppression of glycolysis by citrate-induced inhibition of phosphofructokinase.
Keywords: RMI 14514, MDL 14514, 5-(Tetradecyloxy)-2-furoic acid, 5-(Tetradecyloxy)-2-furancarboxylic acid
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-CR1-2905

Properties

Application: FASN inhibitor
MW: 324.5 D
Formula: C19H32O4
Purity: >98%
Format: Solid

Database Information

CAS : 54857-86-2| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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