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TOFA
TOFA

Item number: Cay10005263-5

Inhibition of fatty acid synthase (FASN) by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines. TOFA is an inhibitor of fatty acid synthesis blocking the synthesis of malonyl-CoA by acetyl-CoA carboxylase (ACC). Both cerulenin (at about 10 µg/ml) and TOFA (at about 1...
Keywords: 5-(Tetradecyloxy)-2-furoic Acid, RMI 14514, 5-(tetradecyloxy)-2-furancarboxylic acid
Application: Bioactive lipid assays
CAS 54857-86-2
MW: 324.5 D
From 50.00€ *
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-10 %
TOFA
TOFA

Item number: AG-CR1-2905-M005

Fatty acid synthase (FASN) inhibitor. Cell permeable, potent, reversible and competitive inhibitor of acetyl-CoA carboxylase (ACC) consequently blocking the synthesis of malonyl-CoA. Useful agent for immunometabolism research. Anticancer agent. Induces apoptosis in a variety of tumor cell lines. Relatively...
Keywords: RMI 14514, MDL 14514, 5-(Tetradecyloxy)-2-furoic acid, 5-(Tetradecyloxy)-2-furancarboxylic acid
Application: FASN inhibitor
CAS 54857-86-2
MW: 324.5 D
39.00€ * From 35.10€ *
Review