THZ531
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).... more
Product information "THZ531"
Description: THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM). Target: CDK. Smiles: CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12. References: Zhang T, et al. Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nat Chem Biol. 2016 Oct,12(10):876-84.
| Supplier: | TargetMol |
| Supplier-Nr: | T4293 |
Properties
| Application: | CDK12 inhibitor, CDK13 inhibitor |
| MW: | 558.07 D |
| Formula: | C30H32ClN7O2 |
Database Information
| CAS : | 1702809-17-3| Matching products |
| KEGG ID : | K08819 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H317, H318, H334, H335, H341, H361, H370, H413 |
| P Phrases: | P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P284, P310, P312, P321, P302+P352, P304+P340, P304+P341, P305+P351+P338, P308+P311, P308+P313, P332+P313, P333+P313, P342+P311, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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