Thioacetazone

Thioacetazone is an antitubercular agent. It is active against M. tuberculosis H37Rv, M. kansasii Bostrom, and M. avium serotype 2 (MICs = 0.3, 0.6, and 20 µg/ml, respectively) but not M. simiae N29 or M. intracellulare serotype 16 (MICs = >40 µg/ml for both). Formulations containing thioacetazone were previously used in the treatment of tuberculosis.Formal Name: N-[4-[[2-(aminothioxomethyl)hydrazinylidene]methyl]phenyl]-acetamide. CAS Number: 104-06-3. Synonyms: Thiacetazone, NSC 3550, SQ 2,321. Molecular Formula: C10H12N4OS. Formula Weight: 236.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml. lambdamax: 330 nm. SMILES: O=C(C)NC1=CC=C(C=C1)C=NNC(N)=S. InChi Code: InChI=1S/C10H12N4OS/c1-7(15)13-9-4-2-8(3-5-9)6-12-14-10(11)16/h2-6H,1H3,(H,13,15)(H3,11,14,16). InChi Key: SRVJKTDHMYAMHA-UHFFFAOYSA-N.