Tepoxalin
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of... more
Product information "Tepoxalin"
Description: Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxygenase (COX) (IC50 = 4.6 microM), rat basophilic leukemia cell (RBL-1) lysate COX (IC50 = 2.85 microM) and COX from intact RBL-1 cells (IC50 = 4.2 microM). Target: Lipoxygenase, COX. Smiles: C(CC(N(C)O)=O)C1=NN(C(=C1)C2=CC=C(Cl)C=C2)C3=CC=C(OC)C=C3. References: McCarthy RJ. Tepoxalin no longer available commercially. Am J Vet Res. 2013 Jul,74(7):948. doi: 10.2460/ajvr.74.7.948. PubMed PMID: 23802664.
| Keywords: | RWJ-20485 , RWJ20485 , ORF20485 , ORF-20485 , RWJ 20485 , ORF 20485 |
| Supplier: | TargetMol |
| Supplier-Nr: | T7724 |
Properties
| Application: | Targets arachidonate 5-lipoxygenase [EC:1.13.11.34] (ALOX5) |
| MW: | 385.84 D |
| Formula: | C20H20ClN3O3 |
Database Information
| CAS : | 103475-41-8| Matching products |
| KEGG ID : | K00461 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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