2 products were found matching "103475-41-8"!
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Tepoxalin
Item number: Cay34849-10
Tepoxalin is a dual inhibitor of COX and 5-lipoxygenase (5-LO, IC50s = 2.84 and 0.15 µM, respectively, in RBL-1 cell lysates). It also inhibits the activity of 12-, but not 15-, LO (IC50s = 4.45 and 146.6 µM for the human platelet and rabbit reticulocyte enzymes, respectively). Tepoxalin reduces the production of...
| Keywords: | ORF 20485, RWJ 20485, 5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-1H-pyrazole-3-propanamide |
| Application: | COX / 5-LO dual inhibitor, antipsoriatic |
| CAS | 103475-41-8 |
| MW: | 385.8 D |
From 58.00€
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Tepoxalin
Item number: TGM-T7724-100mg
Description: Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxygenase (COX) (IC50 = 4.6 microM), rat basophilic leukemia cell (RBL-1) lysate COX...
| Keywords: | RWJ-20485 , RWJ20485 , ORF20485 , ORF-20485 , RWJ 20485 , ORF 20485 |
| Application: | Targets arachidonate 5-lipoxygenase [EC:1.13.11.34] (ALOX5) |
| CAS | 103475-41-8 |
| MW: | 385.84 D |
From 48.00€
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