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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-79942-1 | 100 µl (100 µl) | - | - |
3 - 15 business days* |
1,281.00€
|
||
BPS-79942-2 | 1 ml (500 µl x 2) | - | - |
3 - 15 business days* |
6,027.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome... more
Product information "Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)"
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection. The SARS-CoV-2 Spike Pseudotyped Lentivirus were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions also contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be conveniently measured via luciferase reporter activity. The SARS-CoV-2 Spike pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility.
Keywords: | 2, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 79942 |
Properties
Application: | Viral transduction studies, neutralizing SARS-CoV-2 Spike antibodies screening |
Species reactivity: | SARS-CoV-2 |
Database Information
UniProt ID : | P0DTC2 | Matching products |
Handling & Safety
Storage: | -80°C (avoid repeat freezing and thawing cycles) |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
COVID-19 Research
COVID-19 Research
COVID-19 Research
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