SPI 112Me
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
A prodrug form of SPI 112, inhibits the PTP activity of SHP-2E76K in TK-1 cells, inhibits... more
Product information "SPI 112Me"
A prodrug form of SPI 112, inhibits the PTP activity of SHP-2E76K in TK-1 cells, inhibits Paxillin dephosphorylation, ERK1/2 activation, and cell migration in EGF-stimulated MDA-MB-468 cells at 20 µM. SMILES: COC(C1=CC=CC(N/N=C2C3=CC(S(NCC4=CC=C(C=C4)F)(=O)=O)=CC=C3NC/2=O)=C1)=O. InChi Code: InChI=1S/C23H19FN4O5S/c1-33-23(30)15-3-2-4-17(11-15)27-28-21-19-12-18(9-10-20(19)26-22(21)29)34(31,32)25-13-14-5-7-16(24)8-6-14/h2-12,25,27H,13H2,1H3,(H,26,28,29). InChi Key: AFUSXRUYBQFNGT-UHFFFAOYSA-N
| Keywords: | 3-[(2Z)-2-[5-[[[(4-fluorophenyl)methyl]amino]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]hydrazinyl]-benzoic acid, methyl ester |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 36819 |
Properties
| Application: | SPI 112 prodrug, SHP-2 protein tyrosine phosphatase inhibitor |
| MW: | 482.49 D |
| Formula: | C23H19FN4O5S |
| Purity: | >90% |
| Format: | Solid |
Database Information
| CAS : | 1243685-62-2| Matching products |
| KEGG ID : | K07293 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H315, H319 |
| P Phrases: | P264, P280, P302+352, P305+351+338, P321, P332+313, P337+313, P362+364 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed