SB-657510
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A urotensin II receptor antagonist (Kis = 61, 17, 30, 65, and 56 nM for the human, monkey, cat,... more
Product information "SB-657510"
A urotensin II receptor antagonist (Kis = 61, 17, 30, 65, and 56 nM for the human, monkey, cat, rat, and mouse receptors, respectively), reduces urotensin II-induced increases in the expression of IL1B, IL6, and VCAM1 in EA.hy926 cells at 1 µM, reduces urotensin II-induced adhesion of U937 monocytes to EA.hy926 cells at 1 µM. Formulation: A solid. InChI: InChI=1S/C19H22BrClN2O5S/c1-23-7-6-13(11-23)28-16-8-12(4-5-15(16)21)22-29(24,25)19-10-18(27-3)17(26-2)9-14(19)20/h4-5,8-10,13,22H,6-7,11H2,1-3H3/t13-/m1/s1. InChIKey: KQCZCINJGIRLCD-CYBMUJFWSA-N. SMILES: BrC1=CC(OC)=C(C=C1S(=O)(NC2=CC(O[C@@H]3CCN(C)C3)=C(Cl)C=C2)=O)OC
| Keywords: | 2-bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxy-benzenesulfonamide |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 42321 |
Properties
| Application: | Urotensin II receptor antagonist |
| Immunogen: | 505.81 |
| MW: | 505.81 D |
| Formula: | C19H22BrClN2O5S |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 474960-44-6| Matching products |
| KEGG ID : | K04241 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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