16 products were found matching "K04241"!

The Urotensin II receptor (UT2), also named UTS2R, GPR14, which is expressed in endothelium, smooth muscle, heart and pancreas. Pharmacological inhibition of urotensin II receptor interactions prevents renal insufficiency following renal artery ligation. .

A urotensin II receptor antagonist (Kis = 61, 17, 30, 65, and 56 nM for the human, monkey, cat, rat, and mouse receptors, respectively), reduces urotensin II-induced increases in the expression of IL1B, IL6, and VCAM1 in EA.hy926 cells at 1 µM, reduces urotensin II-induced adhesion of U937 monocytes to EA.hy926...

Urotensin II is a somatostatin-like neuropeptide agonist of the urotensin II receptor (UTR, Ki = 2 nM). It increases intracellular calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM). Urotensin II increases the level of reactive oxygen species (ROS) in pulmonary...

This gene codes high affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system Protein function: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated...

Palosuran is an antagonist of the urotensin II receptor (UTR, IC50s = 3.6 and 1,475 nM for CHO cell membranes expressing human and rat recombinant receptors, respectively). It inhibits contraction of isolated rat aortic rings induced by urotensin II (Cay-24711, Cay-24753) in a concentration-dependent manner....

Protein function: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium]

SB-611812 is an antagonist of the urotensin II receptor (UTR). It binds to recombinant rat UTR (Ki = 121 nM) and inhibits contraction of isolated rat aorta induced by urotensin II (pA2 = 6.59) but not potassium chloride, endothelin-1, angiotensin II, or phenylephrine. SB-611812 (30 mg/kg) decreases myocardial...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat UTS2R. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat UTS2R. Next,...

Recombinant human UTS2R Protein with C-terminal human Fc tag. UTS2R(Met1-Thr51) hFc(Glu99-Ala330), Protein function: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. [The UniProt...

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Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: UTS2R. Antigen Species: Human

Protein function: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium]