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SB-657510
Item number: Cay42321-10
A urotensin II receptor antagonist (Kis = 61, 17, 30, 65, and 56 nM for the human, monkey, cat, rat, and mouse receptors, respectively), reduces urotensin II-induced increases in the expression of IL1B, IL6, and VCAM1 in EA.hy926 cells at 1 µM, reduces urotensin II-induced adhesion of U937 monocytes to EA.hy926...
| Keywords: | 2-bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxy-benzenesulfonamide |
| Application: | Urotensin II receptor antagonist |
| CAS | 474960-44-6 |
| MW: | 505.81 D |
From 216.00€
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SB-657510
Item number: TGM-T12848-100mg
Description: SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting UII-induced inflammatory mediators, such as adhesion molecules, in human vascular...
| CAS | 474960-44-6 |
| MW: | 505.81 D |
From 43.00€
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